农药学学报Issue(2)：225-229,5.DOI:10.3969/j.issn.1008-7303.2015.02.16
烟草甲性信息素及其异构体的简易合成法
Convenient synthesis of the sex pheromone and its isomers of Lasioderma serricorne
摘要
Abstract
The sex pheromone of Lasioderma serricorne and its isomer, 7-hydroxyl-4, 6-dimethylnonan-3-one ( 7 ) , have been synthesized in an overall yield of 61% starting from 2 , 4-dimethylglutaric acid via esterification, reduction, Grignard reaction, mono-etherification, oxidation and deprotection reaction sequence. Another sex pheromone and its isomer 2,6-diethyl-3,5-dimethyl-3,4-dihydro-2H-pyran(8), were obtained by cyclodehydration of 7-hydroxy-4,6-dimethylnonan-3-one. The structures of products were confirmed by NMR and MS spectra spectroscopies.关键词
烟草甲/性信息素/2 ,4-二甲基戊二酸/格氏反应/脱水环化反应Key words
Lasioderma serricorne/sex pheromone/2 , 4-dimethylglutaric acid/Grignard reaction/cyclodehydration分类
农业科技引用本文复制引用
陈海滨,胡武新,杜永均..烟草甲性信息素及其异构体的简易合成法[J].农药学学报,2015,(2):225-229,5.基金项目
浙江省科技厅面上项目(2009C32088) （2009C32088）
