器官移植Issue(2)：93-97,5.DOI:10.3969/j.issn.1674-7445.2015.02.005
肝移植术后中远期胆道并发症47例临床分析
Clinical analysis of 47 cases with mid-and long-term biliary complications after liver transplantation
摘要
Abstract
Objective To investigate the incidence,treatment and outcome of mid-and long-term biliary complications after liver transplantation.Methods Clinical data of 651 patients who underwent liver transplantation at General Hospital of Armed Police Forces from April 2002 to February 2012 were retrospectively studied to analyze the incidence, treatment and outcome of mid-and long-term biliary complications after liver transplantation.Results Among 651 liver transplant cases,47 patients (7.2%) developed mid-and long-term biliary complications.The mean time of onset was 21 months.Forty seven patients underwent 48 cases of treatment in total.Nine cases received anti-inflammatory therapy alone.Fourteen cases were treated with choledochoscope lithotomy,choledochoscope biliary cast or placing the biliary support tube.And 13 cases underwent endoscopic retrograde cholangiopancreatography (ERCP)nephrolithotomy, expanding the bile duct or placing the biliary support tube,including 1 patient was switched to percutaneous transhepatic cholangial drainage (PTCD)due to ERCP failure.Seven cases received drainage by PTCD and 5 cases were treated with anti-inflammatory therapy combined with choledochoscope or PTCD. The total efficacious rate was 92% . Among 3 invalid patients, two patients were treated with secondary liver transplantation and one died.Conclusions The mid-and long-term biliary complications probably occur after liver transplantation.Individualized therapies should be chosen based upon the types and severity of biliary complications,which yields relatively high efficacious rate.Secondary liver transplantation should be performed as necessary.关键词
肝移植/胆道并发症/微创治疗Key words
Liver transplantation/Biliary complications/Interventional management分类
医药卫生引用本文复制引用
蒋伟伟,徐光勋,李俊,陈虹,沈中阳,程明亮,范铁艳,王旭,张庆,陈新国..肝移植术后中远期胆道并发症47例临床分析[J].器官移植,2015,(2):93-97,5.基金项目
国家高技术发展计划（863计划）项目 （）
