器官移植Issue(3):179-183,5.DOI:10.3969/j.issn.1674-7445.2015.03.010
肾移植术后肺部感染预后的 Cox 风险模型分析
Analysis on prognosis of pulmonary infection after renal transplantation by Cox risk model
摘要
Abstract
Objective To analyze the relevant factors affecting prognosis of pulmonary infection after renal transplantation.Methods The clinical data of 40 patients who suffered from pulmonary infection after renal transplantation at the First Affiliated Hospital of Jinan University from January 2000 to December 2010 were analyzed retrospectively.By Cox risk model,single and multi-analysis were performed on 20 possible factors,including age,gender,time of infection,type of infection,white blood cell count,neutrophil ratio, hemoglobin,blood glucose,serum creatinine (Scr),pulmonary infection complicated with acute respiratory distress syndrome or acute pulmonary injury,rejection,blood transfusion,infusion of albumin,infusion of immune globulin,use of ventilator,way of offering oxygen,immunosuppressive regimen,dosage change of immunosuppressant,anti-infection therapeutic regimen and length of stay.Results and Conclusions Triple immunosuppressive therapy without mycophenolate mofetil (MMF ) and increase of neutrophil ratio were independent risk factors for pulmonary infection after renal transplantation.Triple immunosuppressive therapy with MMF combined with early anti-infection therapeutic regimen may improve patient and graft survival of patients with pulmonary infection after renal transplantation.关键词
肾移植/肺部感染/预后/Cox 风险模型Key words
Renal transplantation/Pulmonary infection/Prognosis/Cox risk model分类
医药卫生引用本文复制引用
李文浩,苏泽轩,叶泽兵,黄明坦,陈航..肾移植术后肺部感染预后的 Cox 风险模型分析[J].器官移植,2015,(3):179-183,5.基金项目
广东省临床重点专科建设项目 ()