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肾移植术后肺部感染预后的 Cox 风险模型分析

李文浩 苏泽轩 叶泽兵 黄明坦 陈航

器官移植Issue(3):179-183,5.
器官移植Issue(3):179-183,5.DOI:10.3969/j.issn.1674-7445.2015.03.010

肾移植术后肺部感染预后的 Cox 风险模型分析

Analysis on prognosis of pulmonary infection after renal transplantation by Cox risk model

李文浩 1苏泽轩 2叶泽兵 1黄明坦 1陈航1

作者信息

  • 1. 510317 广州,广东省第二人民医院急诊科
  • 2. 暨南大学附属第一医院泌尿外科
  • 折叠

摘要

Abstract

Objective To analyze the relevant factors affecting prognosis of pulmonary infection after renal transplantation.Methods The clinical data of 40 patients who suffered from pulmonary infection after renal transplantation at the First Affiliated Hospital of Jinan University from January 2000 to December 2010 were analyzed retrospectively.By Cox risk model,single and multi-analysis were performed on 20 possible factors,including age,gender,time of infection,type of infection,white blood cell count,neutrophil ratio, hemoglobin,blood glucose,serum creatinine (Scr),pulmonary infection complicated with acute respiratory distress syndrome or acute pulmonary injury,rejection,blood transfusion,infusion of albumin,infusion of immune globulin,use of ventilator,way of offering oxygen,immunosuppressive regimen,dosage change of immunosuppressant,anti-infection therapeutic regimen and length of stay.Results and Conclusions Triple immunosuppressive therapy without mycophenolate mofetil (MMF ) and increase of neutrophil ratio were independent risk factors for pulmonary infection after renal transplantation.Triple immunosuppressive therapy with MMF combined with early anti-infection therapeutic regimen may improve patient and graft survival of patients with pulmonary infection after renal transplantation.

关键词

肾移植/肺部感染/预后/Cox 风险模型

Key words

Renal transplantation/Pulmonary infection/Prognosis/Cox risk model

分类

医药卫生

引用本文复制引用

李文浩,苏泽轩,叶泽兵,黄明坦,陈航..肾移植术后肺部感染预后的 Cox 风险模型分析[J].器官移植,2015,(3):179-183,5.

基金项目

广东省临床重点专科建设项目 ()

器官移植

OACSCDCSTPCD

1674-7445

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