气象Issue(6)：754-758,5.DOI:10.7519/j.issn.1000-0526.2014.06.012
模拟寒潮对高血压疾病的影响实验研究
Experimental Research of the Impact of Simulated Cold Wave on Hypertension Disease
摘要
Abstract
Based on Zhang Shuyu’s research (2013),the impact of cold wave on hypertension disease is preliminarily discussed through the animal experiments.The cold wave process is simulated in the environ-mental test chamber (TEM1880).At the same time,27 healthy rats are randomly divided into the control group,3 hours beforeTmin(minimum temperature)group,1 hour beforeTmin group,Tmin group,1 hour af-terTmin group,3 hours afterTmin group,cold wave process group,5 hours after the cold wave process group,7 hours after the cold wave process group,respectively.Each group has 3 rats.All the groups ex-cept the control group are exposed to the cold environment and taken out in accordance with the developing progress of cold wave respectively.The following indexes are measured:systolic blood pressure (SBP), heart rate (HR),weight,blood lipid,noradrenaline (NA),angiotensin Ⅱ (Ang Ⅱ),whole blood viscos-ity (WBV),etc.The experimental results show that the air temperature decreases rapidly under the con-trol of the high pressure after cold front leaves in the cold wave process.WBV,NA and Ang Ⅱcan rise to the maximum value at theTmin ,making blood pressure increase in experimental rats in the whole time,and are hard to return to the original level even after the cold wave.关键词
高血压/寒潮天气/影响Key words
hypertension/cold wave/impact分类
天文与地球科学引用本文复制引用
张夏琨,周骥,张书余,马守存,王宝鉴..模拟寒潮对高血压疾病的影响实验研究[J].气象,2014,(6):754-758,5.基金项目
国家自然科学基金项目（40975069）和公益性行业（气象）科研专项（GYHY201106034）共同资助 （）
