四川精神卫生Issue(2)：162-163,176,3.DOI:10.3969/j.issn.1007-3256.2014.02.020
米安色林对首发抑郁症的临床疗效
To observe the efficacy of Mianserin in treatment of patients with first-episode depression
摘要
Abstract
Objective To observe the efficacy and safety of Mianserin in treatment of patients with first-episode depression. Methods 128 patients with first-episode depression were randomly divided into Mianserin group (64 cases treated with Mian-serin)and Fluoxetine group (64 cases treated with Fluoxetine)for 8 weeks.The efficacy was assessed with HAMD and HA-MA,while the adverse reactions were assessed with TESS.Results The effective rate of mianserin group is 92.2%,the effective rate of fluoxetine group is 89.1%.There are no differences between the two groups (P>0.05).But the scores of HAMD and HAMA of Mianserin group were lower than those of Fluoxetine group (P<0.05).Conclusion Mianserin is faster response, less adverse reactions than fluoxetine.It can improve sleep and anxiety symptom in treatment of patients with first-episode de-pression.关键词
米安色林/氟西汀/首发抑郁症Key words
Mianserin/Fluoxetine/First-episode depression分类
医药卫生引用本文复制引用
王华永,李侃虔,马元业..米安色林对首发抑郁症的临床疗效[J].四川精神卫生,2014,(2):162-163,176,3.
