四川精神卫生Issue(5)：430-432,3.DOI:10.3969/j.issn.1007-3256.2014.05.013
首胎次与多胎次的精神分裂症胎次风险研究
The risk study between first and multiple parity of schizophrenia
摘要
Abstract
Objective To compare the difference in demographic data between first and multiple parity and explore the relation-ship between parity and schizophrenia. Methods Demographic data about 500 patients whose ages ranged from 18~40 and which di-agnosis matched the ICD-10 schizophrenia criterion were collected. T test and chi square test were used to analyze the demographic data between first and multiple parity,and using Haldane and Smith formula to explore the risk study between the parity and the schizo-phrenia. Results There was statistical significance included sex distribution (χ2 =8. 48,P=0. 004), family psychotic history(χ2 =4. 34,P=0. 037), prevalence of sibling (χ2 =4. 67,P=0. 03), age of onset (t= -2. 05,P=0. 04),prenatal age of father (t= -8.22,P=0. 00)and mother(t= -9. 71,P=0. 00),maternal abolition or stillbirth frequency(χ2 =69,02,P=0. 00)between two groups. The frequency distribution of parity ( >1) was accounted for 63%, parity ( =1) accounted for 37%. Using the formula of Hal-dane and Smith method,the value of C was 3. 23(C>2,P<0. 01). Conclusion The multiple parity patients were affected seriously by genetic and environment factors than single parity. Multiple parity associated with the prevalence of schizophrenia .关键词
精神分裂症/胎次/人口学资料/风险Key words
Schizophrenia/Parity/Risk分类
医药卫生引用本文复制引用
钟薇..首胎次与多胎次的精神分裂症胎次风险研究[J].四川精神卫生,2014,(5):430-432,3.基金项目
广东省人口和计划生育委员会科研资助项目(20132055)。 （20132055）
