摘要
Abstract
Objective To investigate the results of dexmedetomidine improvement of postoperative delirium following gynaecologic surgery in elderly female patients by general anesthesia. Methods 60 cases of elderly female patients with gynaeco-logic surgery were performed general anesthesia. All cases were randomized into normal dexmedetomidine group ( group A, n=30) and saline group (group B, n=30). The saline and Dexmedetomidine (4μg/ml) was infused with 3μg/(kg·h) for 10 min, then persistently infused with 0. 3μg/( kg·h) to the end of operation in group A and group B, respectively. The following varia-bles were analyzed, including the duration of anesthesia, the recovery time of the autonomous respiration( >10bpm), the extuba-tion time, the richmond agitation-sedation scale(RASS) in extubation, the comfort score after extubation 15min and the CAM Chi-nese reversion after 48 hours of operation. Results There was no significant difference in the duration of anesthesia. The recovery time of the autonomous respiration, the extubation time, the RASS in extubation, the comfort score after extubation 15min were ob-viously different between two groups(all P<0. 05). TThe incidence of postoperative Delirium was significantly lower in group A than one in group B. Conclusion The dexmedetomidine can effectively decrease the incidence of postoperative Delirium following gynaecologic surgery for elderly female patients, the can effectively decrease the agitation rate during recovery period from general anesthesia and a rise in patient satisfaction.关键词
右美托咪定/全麻/老年女性患者/妇科手术/术后谵妄Key words
dexmedetomidine/general anesthesia/elderly female patients/gynaecologic surgery/postoperative delirium分类
医药卫生
