四川医学Issue(7)：881-883,3.
18 F-FDG PET/CT 延迟显像技术在胰腺良恶性病变鉴别诊断中的应用
18 F-FDG PET Delayed Imaging for Differentiating Malignant from Benign Lesions in the Pancreas
杨春敏 1黄海东 1周克 1黄之杰 1舒林 1杨勤1
作者信息
- 1. 成都军区总医院PET/CT中心，神经外科，核医学科，四川成都610083
- 折叠
摘要
Abstract
Objective To explore the value of 18 F-FDG PET delayed imaging in differentiation of malignant from benign lesions in the pancreas. Methods Forty-two patients with clinically suspected malignant pancreatic lesions including 27 cases with pancreatic cancer and 15 cases with chronic pancreatitis. The finally definite diagnosis was obtained by pathology and imageologic or clinical follow-up. All patients underwent 18 F-FDG PET 1h early and 2h delayed imaging after intravenous injection of 252 ~356 MBq of 18 F-FDG. The standardized uptake value(SUV) was calculated for both time points, and retention index(RI) was al-so calculated. Results The SUV of pancreatic cancer in delayed imaging were significantly higher in early imaging(P < 0. 01). However,the SUV of pancreatitis in delayed imaging were significantly lower in early imaging(P < 0. 01). Take early imaging SUV > 2. 5 as standard, the sensitivity, speciality and accuracy of diagnosis was 83. 3% , 76. 2% and 81. 0% respectively. Take delayed imaging SUV > 2. 5 as standard, the sensitivity, speciality and accuracy of diagnosis was 88. 1% , 81. 0% and 85. 7% re-spectively. Take RI > 15% as standard, the sensitivity, speciality and accuracy of diagnosis was 90. 5% , 85. 7% and 88. 1% . When combining delayed imaging SUV > 2. 5 and RI > 15% as standard,the sensitivity, speciality and accuracy of diagnosis was 95. 2% , 88. 1% and 92. 9% respectively. Conclusion 18 F-FDG PET delayed imaging is a reliable imaging protocol fordifferen-tiating malignant from benign lesions in the pancreas. Combining delayed imaging SUV and RI can improve the accuracy of diagno-sis.关键词
胰腺肿瘤/PET/ CT/延迟显像/脱氧葡萄糖Key words
pancreatic neoplasms/PET/delayed imaging/deoxyglucose分类
医药卫生引用本文复制引用
杨春敏,黄海东,周克,黄之杰,舒林,杨勤..18 F-FDG PET/CT 延迟显像技术在胰腺良恶性病变鉴别诊断中的应用[J].四川医学,2014,(7):881-883,3.
