四川医学Issue(9)：1118-1120,3.
赛机宁对脑瘫患儿脊神经根诱发肌电图监测的影响
Effect of Nimbexonevoked Electromyography Monitoring of Spinal Nerve Rootin children with Cerebral Palsy
摘要
Abstract
Objective To investigate the effect of nimbex different peripheral neuromuscular blockade( NMB) on evoked electromyography monitoring( EEMG) of spinal nerve root in children with cerebral palsy. Methods Twenty ASA physical statusⅠorⅡchildren with cerebral palsy of both sexes, aged 3-12 yr, scheduled for elective functional selectivity of lumbar posterior rhi-zotomy, were included in the study. After induction of anesthesia, the spinal nerve root was accepted continuous electrical stimula-tion for 3 times with the electrophysiological monitoring of Nicolet Endeavor-CR 16 channel, interval 5s, the stimulus intensity of 3. 50 mA. The average amplitude and latency ofEEMGwere recorded as basic values. Intravenously injection nimbex 0. 05mg/kg,then the spinal nerve root was accepted continuous electrical stimulation for 3 times as the same intensity of stimulation and the inter-val time when NMB were 100%, 75%, 50%, 25%. The average amplitude and latency were recorded respectively,then analyzed the relationship betweenamplitude retention ratio andlatency with nimbex different NMB. Results With the decrease of NMB, the amplitude retention ratio was increases, the amplitude retention ratio ( Y) and NMB ( X) showed negative correlation, the correlation coefficient R was 0. 960 a(P<0. 01). When NMB was 50% ~ 100%, the latency was significantly prolonged than basic values, the latency( Y) and NMB( X) is positive correlation, the correlation coefficient R was 0. 481 a ( P< 0. 01 ) . Conclusion The nimbex would affect the spinal nerve root EEMG. With the degree of NMB gradually decreased, the amplitude retention ratio was increases and the latency was shortening gradually.关键词
赛机宁/N2胆碱受体阻断药/肌电图/术中监测/脊神经根/脑性瘫痪/儿童Key words
Nimbex/N2-cholinoceptor blocking drugs/electromyography/intraoperative monitoring/spinal nerve root/cere-bral palsy/children分类
医药卫生引用本文复制引用
刘建波,赵泽宇,张蓉,王馨雪,黄建盛,程庆..赛机宁对脑瘫患儿脊神经根诱发肌电图监测的影响[J].四川医学,2014,(9):1118-1120,3.基金项目
四川省卫生厅科研课题(编号:130250) （编号:130250）
