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复合超滤对瓣膜置换术后心功能的影响

杨小云 徐明元 徐贵森 蔡钦 宋恒昌

四川医学Issue(9):1153-1155,3.
四川医学Issue(9):1153-1155,3.

复合超滤对瓣膜置换术后心功能的影响

The Effect of Compound Ultrafiltration on Postoperative Cardiac Function in Cardiac Valve Replacement

杨小云 1徐明元 1徐贵森 1蔡钦 1宋恒昌2

作者信息

  • 1. 成都军区总医院急诊科,四川 成都610083
  • 2. 沈阳军区总医院心外科,辽宁 沈阳110016
  • 折叠

摘要

Abstract

Objective To study the clinical evaluation of using compound ultrafiltration on effect of cardiac function in cardiac valve replacement under ECC. Methods 60 patients who underwent mitral valve replacement under ECC were randomly divided into four group:conventional ultrafiltration group ( CUF, n=15 ) , modified ultrafiltration group ( MUF, n=15 )、zero-bal-anced ultrafiltration(ZUF,n=15)and Compound Ultrafiltration(M +Z,n =15). The patient’s time of mechanical ventilation (MAT)、Cardiac index(CI) and the concentrations of tumor necrosis factor-α(TNF-α)and interleukin-8(IL-8)in the four groups were respectively monitored . Results After operation,the time of mechanical ventilation in M+Z group was shorter than that in MUF group、ZUF group and CUF group;At 2h、12h.、24h and48h after operations the CI in M+Z group was higher than that in the ZUF group、MUF group and CUF group(P<0. 05);At 0h、2h、12h and 24h after opertitions,The concentrations of TNF-α and IL-8 in M+Z group and ZUF group was lower significantly than that in the MUF group and CUF group(P<0. 05). Conclusion Compared to the ultrafiltration with single method, Compound ultrafiltration can decrease inflammatory response, improve batter postoperative cardiac function of patients in cardiac valve replacement under ECC.

关键词

复合超滤/体外循环/心功能/瓣膜置换

Key words

compound ultrafiltration/extracorporeal circulation/cardiac function/cardiac valve replace

分类

医药卫生

引用本文复制引用

杨小云,徐明元,徐贵森,蔡钦,宋恒昌..复合超滤对瓣膜置换术后心功能的影响[J].四川医学,2014,(9):1153-1155,3.

四川医学

OACSTPCD

1004-0501

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