摘要
Abstract
Objective To investigate the clinical efects of Sildenafil for treating persistent pulmonary ypertension. Meth-ods Selected 32 patients diagnosed with PPHN in our department between January 2012 and April 2013,then,According to whether using sildenafil divided them into two groups( the sildenafil group were 15 cases,control group were 17 cases). the control group given general treatment,the sildenafil group were treated with sildenafil on the basis of general treatment,the use of sildenafil dose was 0. 5-1. 0 mg/kg,drop into the inside of the feed tube. Before using sildenafil and afer three days,observed the change of arterial blood PaCO 2﹑PaO 2﹑SaO 2 and PAMP. we also calculate the total effective. Results After three days,the arterial blood PaO 2﹑SaO 2 of the sildenafil group were significantly increased,the arterial blood PaCO 2﹑PAMP were decreased significantly compared with the control group(P <0. 05). The total effective of the sildenafil group was higher than the control group(P <0. 05 ) . Conclusion Sildenafil for treating PPHN can effectively reduce the pulmonary artery pressure,improve blood oxygen satu-ration,has a good therapeutic effect.关键词
西地那非/持续性肺动脉高压/新生儿Key words
sildenafil/persistent pulmonary ypertension/newborn分类
医药卫生
