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子宫动脉栓塞与甲氨蝶呤联合氟尿嘧啶治疗子宫切口妊娠的对比研究

陈小芬 陈洪彬 周洪贵

四川医学Issue(10):1292-1294,3.
四川医学Issue(10):1292-1294,3.

子宫动脉栓塞与甲氨蝶呤联合氟尿嘧啶治疗子宫切口妊娠的对比研究

Comparative Study of Uterine Artery Chemoembolization and Methotrexate with 5-fluorouracil in the Treatment of Cesarean Scar Pregnancy

陈小芬 1陈洪彬 1周洪贵1

作者信息

  • 1. 川北医学院附属医院妇产科,四川 南充637000
  • 折叠

摘要

Abstract

Objective To compare the efficacy of uterine artery chemoembolization( UAE) and methotrexate( MTX) with 5-fluorouracil(5-Fu)in the treatment of cesarean scar pregnancy(CSP). Methods The clinical data of 100 cases with CSP were analyzed retrospectively. According to the preference of the patient,the 100 cases were divided into the interventional embolization group and the systemic medication group,Clinical indicators after treatment were compared between the two groups. Results The interventional embolization group was less vaginal bleeding,shorter hospitalization time and serum β-hCG dropped to normal time than the systemic medication group with significant differeence ( P <0. 05 ) . The success rate of the interventional embolization group was 96. 0%(48/50),and the systemic medication group was 86. 0%(43/50),but the success rate between the two groups differeence was not significant(P>0. 05). Adverse reactions between the two groups differeence was not significant(P>0. 05). During the follow-up period,no significant difference in the recovery time of the mental cycle and the hormone levels were found between the two groups(P>0. 05). Conclusion Curettage after UAE is safer and more effective for CSP,while this needs higher technology requirement;Curettage after the systemic medication of MTX and 5-Fu can be more suitably adopted in the primary hospital with lower technology requirement and without special device of interventional treatment.

关键词

子宫动脉栓塞术/清宫术/MTX/5-Fu/子宫切口妊娠

Key words

uterine artery chemoembolization/curettage/methotrexate/fluorouracil/cesarean scar pregnancy

分类

医药卫生

引用本文复制引用

陈小芬,陈洪彬,周洪贵..子宫动脉栓塞与甲氨蝶呤联合氟尿嘧啶治疗子宫切口妊娠的对比研究[J].四川医学,2014,(10):1292-1294,3.

四川医学

OACSTPCD

1004-0501

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