四川医学Issue(10)：1357-1359,3.
同型半胱氨酸、叶酸、维生素B6及维生素B12与糖尿病并发症的相关性研究
The Relationships between Homocysteine、Folic Acid、Vitamin B6、Vitamin B12 Levels and Diabetic Complications
黄激扬 1晏江丽 1徐静 1查小红1
作者信息
- 1. 眉山市中医医院检验科，四川 眉山620000
- 折叠
摘要
Abstract
Objective To explore the clinical significance and compare the difference of homocysteine( HCY)、folic acid (FA)、vitamin B6(VitB6)、vitamin B12(VitB12)levels in kinds of diabetic mellitus(DM)and healthy subjects. Methods Our study is planned to evaluate HCY、FA、VitB6、VitB12 levels in 15 DM cases with peripheral vascular disease、13 DM cases with cerebral infarction、23 DM cases with nephropathy、18 DM cases with peripheral neuropathy、27 DM cases with retinopathy、15 DM cases with peripheral vascular disease、29 DM cases with no complications and 33 healthy subjects. Results HCY levels was found to be significantly higher and FA、VitB6、VitB12 were found to be significantly lower in DM groups than healthy subjects group(P<0. 05),especially in DM with cerebral infarction group or DM with peripheral vascular disease group(P<0. 01). There is a correlation between HCY and FA、VitB6、VitB12 in DM patients either(P<0. 05),especially in DM with cerebral infarction group(P<0. 01). What’s more,HCY levels was lower and FA levels was higher in intervention group when compared with un-in-tervention group. Conclusion The levels of HCY、FA、VitB6、VitB12 were found to be correlated with DM and complications. Sup-plement of FA and VitB12 could play a role in the prognosis of the disease.关键词
同型半胱氨酸/叶酸/维生素B6/维生素B12/糖尿病/并发症Key words
HCY/FA/VitB6/VitB12/diabetic mellitus/complications分类
医药卫生引用本文复制引用
黄激扬,晏江丽,徐静,查小红..同型半胱氨酸、叶酸、维生素B6及维生素B12与糖尿病并发症的相关性研究[J].四川医学,2014,(10):1357-1359,3.
