四川医学Issue(12)：1519-1521,3.
绵阳市老年冠心病患者高同型半胱氨酸血症界定值研究
The Cutoff Point of Hyperhomocysteinemina in Elder with Coronaryheart Disease(CHD) of Mianyang
摘要
Abstract
Objective Study the cutoff point ofhyperhomocysteinemina ( HHcy) in elder with coronaryheart disease (CHD) of Mianyang. Methods The homocysteine (Hcy) was measured in 427 elderly patients who were suspected ashaving CHD. The cutoff point of HHcy was determined by receiver operator characteristic curve. According to the cutoff point,all patients were divided intohigh-risk group and low-risk group. Cornary angiograghy (CAG) was performed in all patients and the number of coronary Gensini's score was used for evaluate the severity of atherosclerosis in patients diagnosed as CHD. Results The best cut-off point of HHcy was 23. 19μmol/ L and its sensitivity was 77. 3% and 69. 7% ,respectively. 269 patients were diagnosed as CHD inhigh-risk group,significantlyhigher than that in low -risk group(41 patients,91. 2% vs. 35. 7% P < 0. 001). The average num-ber of coronary Gensini's score ofhigh-risk group higher than low -risk group (33. 43 ± 4. 22 vs. 9. 51 ± 2. 89 P < 0. 01). Conclu-sion The cutoff point of HHcy in elder with CHD of Mianyang was 23. 19μmol/ L.关键词
老年/冠心病/高同型半胱氨酸血症Key words
elder/coronaryheart disease/hyperhomocysteinemina分类
医药卫生引用本文复制引用
王羽..绵阳市老年冠心病患者高同型半胱氨酸血症界定值研究[J].四川医学,2014,(12):1519-1521,3.基金项目
四川省医学会基金课题(编号:SHD11-11) （编号:SHD11-11）
