摘要
Abstract
Objective To investigate the characteristics of multi-slice spiral CT perfusion imaging in patients with acute cerebral infarction and its relationship with clinical prognosis. Methods Forty patients who met the inclusion criteria were selected to undergo CT perfusion imaging,and their cerebral blood flows ( CBFs),cerebral blood volumes ( CBVs),mean transit times (MTTs) and transit time peaks (TTPs) were calculated. Clinical neurologic impairment was assessed with the National Institutes of Health Stroke Scale (NIHSS) and the potential recuperation ratio (PRR) of the ischemic brain tissue and the neural functional recovery ratio were calculated on admission and at day 14 after treatment,respectively. Results CBV and CBF were lowest in cen-tral cerebral infarction lesions,highest contralaterally and median in the ischemic penumbra,and the difference was statistically sig-nificant (P < 0. 05). MTT and TTP werehighest in central cerebral infarction lesions,lowest contralaterally and median in the is-chemic penumbra,and the difference was statistically significant (P < 0. 05). PRR was independent of patients’ NIHSS scores on admission (r = - 0. 227,P > 0. 05),negatively dependent of those at day 14 after treatment (r = - 0. 340,P < 0. 05) and positive-ly dependent of patient’s neural functional recovery ratio (r = 0. 467,P < 0. 05). Conclusion Multi-slice spiral CT perfusion im-aging can reflecthemodynamic changes in acute cerebral infarction lesions and their perihemodynamic changes. PRR is closely de-pendent of the neural functional recovery. It can serve as a reliable theoretical basis for clinical treatment.关键词
急性脑梗死/脑灌注成像/体层摄影术/X 线计算机Key words
acute cerebral infarction/cerebral perfusion imaging/tomograthy/X-ray computed分类
医药卫生
