四川医学Issue(3)：291-295,5.DOI:10.16252/j.cnki.issn1004-0501-2015.03.008
累及免疫正常宿主肠道的播散型组织胞浆菌病3例
Intestinal Involvement in Disseminated Histoplasmosis:3 Cases of Immunocompetent Host
朱林林 1郭天娇 1王瑾 1王一平 1杨锦林1
作者信息
- 1. 四川大学华西医院消化内科，四川 成都610041
- 折叠
摘要
Abstract
Objective To summarize the characteristics of intestinal lesions in 3 cases of immunocompetent host with dis-seminated histoplasmosis. Methods Retrospective analysis of clinical and endoscopic features was carried out in 3 cases of im-munocompetent host with disseminated histoplasmosis during 2005 and 2014 at our hospital. Results Fever,abdominal pain, dis-tention,hepatosplenomegaly,lymphadenopathy are the most common nonspecific symptoms and signs. Lesions which involving the colon and terminal ileum were manifested as diffuse or segmental mucosal nodular with or without erosion,shallow ulcers. The con-firmed diagnosis depended on multiple site biopsy and pathogenic culture. All patients were treated with amphotericin B deoxy-cholate and Itraconazole,it was effective in 2cases while the other one were lost to follow-up. Conclusion This rare disease is easy to be misdiagnosis. Gastrointestinal physicians should pay attention to the characteristics,biopsy and pathogen culture should be done if lesions had been found.关键词
播散型组织胞浆菌病/肠道/免疫正常宿主Key words
disseminated histoplasmosis/intestinal/immunocompetent host分类
医药卫生引用本文复制引用
朱林林,郭天娇,王瑾,王一平,杨锦林..累及免疫正常宿主肠道的播散型组织胞浆菌病3例[J].四川医学,2015,(3):291-295,5.
