摘要
Abstract
Objective To explore the value of APACHE Ⅱ, serum procalcitonin(PCT)and interleukin-6(IL-6)in pre-dicting prognosis of patients with severe pneumonia. Methods 126 cases of patients with severe pneumonia who were received me-chanical ventilation from December 2013 to May 2014,79 patients were enrolled as the survival group, and 47 patients were en-rolled as the non-survival group. The dynamic change of APACHE II score, serum PCT and IL-6were observed at day 1,3,5,7 and the day of discharge from ICU or death. Blood specimens were collected at the same points. Results APACHE II score,ser-um PCT in survival group were(20. 12 ± 5. 74)scores,(10. 36 ± 3. 08)ng /mL, and were(25. 66 ± 6. 73)scores,(13. 17 ± 3. 99) ng /mL in death group respectively. Significant differences( P<0. 05)were found between two groups of data. Within the period, APACHE II score and the serum PCT of the survival group decreased,while the non-survival group increased. The serum IL-6 of the two groups decreased gradually. APACHE II was positively correlated with serum procalcitonin. Conclusion The dynamic change of APACHE II score, serum PCT and IL-6can be one of the references to evaluate the condition and prognosis of patients with severe pneumonia.关键词
APACHE Ⅱ评分/降钙素原/白介素-6/重症肺炎Key words
APACHE II score/procalcitonin/interleukin-6/severe pneumonia分类
医药卫生
