四川医学2015，Vol.36Issue(5)：681-683,3.DOI:10.16252/j.cnki.issn1004-0501-2015.05.028
老年慢性阻塞性肺疾病血清D-二聚体变化的临床意义
The Changes of Serum D-dimer in The Elderly Patients with Chronic Obstructive Pulmonary Disease and Its Signifi-
cance
陈红 1李小惠 1李为民 2陈勃江2
作者信息
- 1. 四川省医学科学院·四川省人民医院干部科,四川 成都610072
- 2. 四川大学华西医院呼吸内科,四川 成都610041
- 折叠
摘要
Abstract
Objective To investigate the clinical significance of changes of serum D-dimer for the elderly patients with a-cute exacerbation of chronic obstructive pulmonary disease( AECOPD) before and after treatment. Methods 40 elderly patients with AECOPD were randomly selected,The serum D-dimer level of these 40 subjects were determined before and after treatment. 40 healthy persons were selected for the healthy control group. The arterial PaO 2 was detected for the elderly patients with AECOPDbefore treatment. The association between serum D-dimer and PaO 2 was analyzed. Results The serum D-dimer level in AECOPD group was higher than the control group. The difference was considered significant(P＜0. 05). The serum D-dimer level with elderly AECOPD patients after treatment was lower than those before treatment ( P＜0. 05 ) . Serum D-dimer level was negatively correlated with PaO2(P＜0. 05). Conclusion The prothrombotic state probably exists in COPD patients. Serum D-dimer level might reflect the severity of COPD and coagulation status.关键词
慢性阻塞性肺疾病/D-二聚体/动脉血氧分压Key words
chronic obstructive pulmonary disease/D-dimer/PaO 2分类
医药卫生引用本文复制引用
陈红,李小惠,李为民,陈勃江..老年慢性阻塞性肺疾病血清D-二聚体变化的临床意义[J].四川医学,2015,36(5):681-683,3.
