摘要
Abstract
Objective To investigate the clinical effect of levosimendan on septic shock and myocardial depression. Methods 51 cases of septic shock with myocardial depression patients were randomly divided into treatment group and control group. The control group received Milrinone treatment on the basis of the treatment. Treatment group received levosimendan treat-ment on the basis of the treatment. To observe the therapeutic effect of two groups of patients. Results Compared with the control group,after the treatment in the treatment group,SVI,CI,LVSWI were significantly increased(P<0. 05),HR,Lac,NT-proBNP, EVLWI were significantly decreased(P<0. 05). Compared with the treatment group,after the treatment in the control group,SVRI was significantly increased(P<0. 05). Compared with the control group,in the treatment group,the mechanical ventilation time and the length of stay in ICU,were significantly shorter(P<0. 05),the two groups showed no significant difference in hospital mor-tality(P>0. 05). Conclusion levosimendan can improve heart function,reduce extravascular lung water,improve tissue perfu-sion and oxygen metabolism,reduce mechanical ventilation time,shorten the length of stay in ICU of patients with septic shock and cardiac depression.关键词
左西孟旦/脓毒症休克/心肌抑制/脉波指示剂连续心排血量监测Key words
levosimendan/septic shock/myocardial depression/pulse indicating continuous cardiac output monitoring分类
医药卫生
