摘要
Abstract
Objective:To investigate fluoxetine treatment of elderly patients with post -stroke depression and its impact on clinical out-comes in patients with neurological rehabilitation role .Methods:120 patients with CT or head MRI diagnosis of stroke and was associated with depression in elderly patients were randomly divided into two groups and the control group of 60 cases , in which the control group were treated with conventional nervous system drugs and supportive treatment were observed in the control group group on the basis of ap -plication of fluoxetine treatment , continuous treatment for 3 months .Patients were followed for six months , depressive symptoms were ob-served , nerve function and motor function recovery situation .Results:Compared with before treatment , after treatment , the observation group SAS, SDS scores were significantly decreased (P <0.05), while the control group before and after treatment SAS , SDS score did not change (P>0.05).Compared with the control group , the observation group patients after the first one month , two months, three months, six months Barthel Index scores were significantly better than the control group , the difference was statistically significant ( P <0.05).Compared with the control group , patients in observation group after intervention a month , two months, three months, six months neurological deficit score (MESSS) was significantly better than the control group , the difference was statistically significant (P <0.05). Conclusion:Elderly patients with post -stroke depression fluoxetine treatment could effectively improve depressive symptoms in patients , improve patient life skills , promote neurological rehabilitation , might be conducive to the prognosis of patients .关键词
老年脑卒中/抑郁症/神经功能Key words
Elderly stroke/Depression/Neurological分类
医药卫生
