中国伤残医学Issue(13)：21-23,3.DOI:10.13214/j.cnki.cjotadm.2014.13.013
口服质子泵抑制剂治疗高出血风险消化性溃疡出血
Oral Proton Pump inHibitors Treat High-risk Peptic Ulcer Bleeding
王志兵 1周俊2
作者信息
- 1. 兵器工业北京北方医院内科，北京 100089
- 2. 中国康复研究中心北京博爱医院消化内科
- 折叠
摘要
Abstract
Objective:After successful endoscopic hemostasis ,high-risk patients with peptic ulcer bleeding usually were given proton pump inhibitor ( PPI) via intravenous as adjuvant pharmacotherapy , usually with high -dose PPI or normal dose .Now some study found that after successful endoscopic hemostasis , compare with PPI intravenous group , peptic ulcer bleeding patients frequent oral PPI can reach intragastric pH above 6, only delay approximately 1 hour, frequent oral PPI provided similar antisecretory effect .In some clinical study , there was no significant difference among PPI frequently oral group and intravenous group in recurrent bleeding , hospital stay , vol-ume of blood transfusion , surgical interventions and mortality rate .So, after successful endoscopic hemostasis , patients frequently oral PPI could be another choice as adjuvant pharmacotherapy .关键词
消化性溃疡/上消化道出血/质子泵抑制剂Key words
Peptic ulcer/Upper gastrointestinal bleeding/Proton pump inhibitors分类
医药卫生引用本文复制引用
王志兵,周俊..口服质子泵抑制剂治疗高出血风险消化性溃疡出血[J].中国伤残医学,2014,(13):21-23,3.
