中国伤残医学Issue(3)：12-14,3.DOI:10.13214/j.cnki.cjotadm.2015.03.008
丙泊酚全麻对乳腺癌术后复发的影响研究
The Effect of General Anesthesia with Propofol on Postoperative Recurrence in Breast Cancer
黄柯冰 1袁磊 1黄杰 1李凤仙1
作者信息
- 1. 陕西省汉中市中心医院，陕西汉中 723000
- 折叠
摘要
Abstract
Objective:To explore the use of propofol effect implementation of general anesthesia in patients with breast cancer recur -rence.Method:Select 40 cases of I-II of breast cancer patients in our hospital for treatment , ASA I-II-level, all patients with General anesthesia and surgery , observing the change of angiogenesis factor before and after operation , including VEGF -C, bFGF, TGFβand PIGF, and select the same period medical examination 40 healthy people as the normal controls. Results:VEGF-C and PIGF preoperative increased significantly (P<0.05), bFGF, TGFβreduced (P<0.05), but still higher than normal control groups;and there were posi-tive correlation between P/W and VEGF-C and bFGF, and TGFβand P/W had negative correlation. Conclusion:The use of different do-ses of propofol in breast cancer patients after general anesthesia had different levels of impact on various angiogenesis factors , thus affecting the recurrence of tumors , so look for the best implementation of general anesthesia of propofol dose of great clinical was significance.关键词
丙泊酚/乳腺癌/血管生成因子Key words
Propofol/Breast cancer/Angiogenesis factors分类
医药卫生引用本文复制引用
黄柯冰,袁磊,黄杰,李凤仙..丙泊酚全麻对乳腺癌术后复发的影响研究[J].中国伤残医学,2015,(3):12-14,3.
