中国伤残医学Issue(6)：16-19,4.DOI:10.13214/j.cnki.cjotadm.2015.06.011
调强放疗联合同步化疗治疗中晚期宫颈癌的研究
Study on treatment metaphase or advanced stage of cervica cancer was used by intensity-modulated radiotherapy with synchronous chemotherapy
黄瑞文 1蔡永广 1李能平 1梁文胜1
作者信息
- 1. 广东省农垦中心医院放疗科，广东 湛江 524002
- 折叠
摘要
Abstract
Objective: To Investigate the curative effect, adverse reaction, survival conditions and mend matters of life of pa-tients in treatment metaphase or advanced stage of cervica cancer which was used by intensity-modulated radiotherapy with synchro-nous chemotherapy. Methods: Metaphase or advanced stage of cervica cancer patients who receive and cure from January 2009 to June 2013, They were divided into experimental group (66 cases) and control group (42 cases). Treatment Protocols of experi-mental group were paclitaxel and cisplatin combined with synchronous Intensity -Modulated radiotherapy, and control group were paclitaxel and cisplatin combined with three-dimensional conformal radiotherapy. The curative effect, 1 - year survival rate, 1 -year disease free surviva, adverse reaction, mend matters of life were be statisticsed, using chi-square test to analyze the data. Re-sults: The experimental group's complete remission rate was 84. 85%, which was higher than the control group's 71. 43% (but P>0. 05). The experimental group's incidence of acute gastrointestinal adverse reactions was 45. 45%, which was significantly lower than the control group's 66. 67% (P<0. 05). The experimental group's incidence of anemia was 43. 94%, which was significantly lower than the control group's 64. 29% (P<0. 05). The experimental group's incidence of platelets abnormal was 33. 33%, which significantly lower than the control group's 52. 38% (P<0. 05). The incidence of irradiation cystitis and factitial proctitis were 6. 06% and 10. 61% in experimental group, and the incidence of irradiation cystitis and factitial proctitis were 26. 19% and 30. 95%in control group, they were all significant differences between the two groups (P<0. 05). Conclusion: The therapeutic effect is clear-cut which use intensity-modulated radiotherapy to treat the metaphase or advanced stage of cervica cancer, this therapeutic schedule although could reduce the rate of adverse reaction and improve sufferer's living quality,but curative effect and patient surviv-al rates are indifference to three-dimensional conformal radiotherapy therapeutic schedule.关键词
宫颈癌/调强放疗Key words
Cervica cancer/Intensity-modulated radiotherapy分类
医药卫生引用本文复制引用
黄瑞文,蔡永广,李能平,梁文胜..调强放疗联合同步化疗治疗中晚期宫颈癌的研究[J].中国伤残医学,2015,(6):16-19,4.
