中国伤残医学Issue(6)：23-24,2.DOI:10.13214/j.cnki.cjotadm.2015.06.015
甲磺酸伊马替尼治疗慢性粒细胞白血病的临床观察
Clinical observation of imatinib in treatment of patiengts with chronic myeloid leukemia
晋红丽 1韩艳玲 1张艳影1
作者信息
- 1. 铁法煤业集团总医院血液科，辽宁 铁法 112700
- 折叠
摘要
Abstract
Objective:To observe the effect of imatinib on patients with Philadelphia chromosome-positive( Ph-positive) of chronic myeloid leukemia . Methods: Forty-six patients with Philadelphia chromosome-positive(Ph-positive) of chronic myeloid leukemia were rangomly divided into two groups,the treatment group (29 cases) and the control group (19 cases) Patients in the treatment group were treated with imatinib. the patients in the control group were treated with hydroxyurea(hu) ,interferon-α(IFN-α). The response rates of hematology and cytogene were compared after treatment. Results:The complete respse rate of hematology and the key response rate of cytogenge in the treatment group were higher than those in the control group (p<0. 05). Conclusion: Imainib significantly could im-prove hematology and cytogenetic response rates ,quality of life,and progression-free survival for patients with Ph-positive of chronic myeloid leukemia .关键词
慢性粒细胞白血病/费城染色体/伊马替尼/干扰素~α/羟基脲Key words
Chronic myeloid/leukemia matinib/ydroxyurea( hu)/interferon-α( IFN-α)分类
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晋红丽,韩艳玲,张艳影..甲磺酸伊马替尼治疗慢性粒细胞白血病的临床观察[J].中国伤残医学,2015,(6):23-24,2.
