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首页|期刊导航|中国伤残医学|白藜芦醇保护少弱精子优选过程氧化应激损伤的研究

白藜芦醇保护少弱精子优选过程氧化应激损伤的研究

王莉莉 张铁汉 申素芳

中国伤残医学Issue(10):13-14,2.
中国伤残医学Issue(10):13-14,2.DOI:10.13214/j.cnki.cjotadm.2015.10.009

白藜芦醇保护少弱精子优选过程氧化应激损伤的研究

Study on protection role of resveratrol for oligo-asthenic sperms(OAS) duingi n-vitro process of ptimization

王莉莉 1张铁汉 1申素芳1

作者信息

  • 1. 新乡医学院第三附属医院,河南新乡 453000
  • 折叠

摘要

Abstract

Objective:To study the protection role of resveratrol for oligo-asthenic sperms( OAS) duing in-vitro process of ptimiza-tion Methods:According to the WHO standard,51 OSA sample were selected.The sample were divided into 3 group, with 500ml in each group.control group which was only pured EBSS ,centrifugal control group ,centrifugal and resveratrol group .Each treated sperm Was detected with reactive oxygen species( ROS) and malondialdehyde( MDA) concentration.Then we did the analysis of variance of random-ized block design and multiple comparison.This research Was be divided for oligoasthenozoospermia sperm part and normal sperm part. Results:In oligo-asthenic sperms, ROS and MDA levels of centrifugal control group were significantly increased than control group;in oligo-asthenic sperms, ROS and MDA levels of centrifugal and resveratrol group were significantly lower than centrifugal control group . Conclusion:During the centrifugal process, adding resveratrol in vitro could reduce the peroxidative damage of oligoasthenozoospermia sperm .

关键词

少弱精子/白藜芦醇/优选/氧化应激/ROS/MDA

Key words

Resveratrol/optimization/Oxidative Stress/oligo-asthenic sperms

分类

医药卫生

引用本文复制引用

王莉莉,张铁汉,申素芳..白藜芦醇保护少弱精子优选过程氧化应激损伤的研究[J].中国伤残医学,2015,(10):13-14,2.

基金项目

河南省医学科技攻关计划项目,编号201303112 ()

中国伤残医学

1673-6567

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