摘要
Abstract
Objective:Analysis of low-dose quetiapine combined clinical efficacy of sertraline in patients with anxiety, depression, insomnia, and provide reference for clinical diagnosis and treatment.Methods:Our hospital will comply with ICD-10 depressive episode or recurrent depression diagnostic criteria as the observed object 160 patients were randomly divided into sertraline joint quetiapine group and sertraline alone group, 80 cases in each group.Comparing two groups of patients one week, two weeks, four weeks, eight weeks of the Hamilton Depression Scale ( HAMD) and Hamilton Anxiety Scale ( HAMA) and HAMD sleep factor case.Results:Two groups of pa-tients before treatment and after treatment one week HAMD score, HAMA and HAMD score sleep factor scores showed no significant difference (P＞0.05), the treatment of two weeks, four weeks, eight weeks later, observed each item score than the control group group, the difference was statistically significant ( P ＜0.05);treatment, one week, two weeks, four weeks, eight weeks of HAMD, HA-MA reduction rate difference was statistically significant, and the reduction rate of the observation group than the control group, the differ-ence was statistically significant (P ＜0.05).Conclusion: Sertraline in combination with low-dose quetiapine in the treatment of de-pression in patients with anxiety and insomnia better than sertraline alone treatment effect is obvious, it is worth learning from.关键词
舍曲林/喹硫平/抑郁/焦虑/失眠Key words
Sertraline/Quetiapine/dDepression/Anxiety/Insomnia分类
医药卫生
