泮托拉唑钠肠溶微丸胶囊的处方工艺研究OA
Study on formulation and preparation of pantoprazole Enteric - coated pellet Capsules
目的：研制泮托拉唑钠肠溶微丸胶囊。方法采用流化床包衣法制备泮托拉唑钠肠溶微丸，将制备好的微丸装入胶囊即得泮托拉唑钠肠溶微丸胶囊。结果胶囊在人工胃液中耐酸良好，在人工肠液中能够迅速溶出。结论该工艺简单易行、重现性良好、生产周期短、成本低、适合工业化生产。
Objective To develop the prescription processing of Pantoprazole Enteric - coated Pellet Capsules (PECPC). Methods The pantoprazole enteric - coated pellets were prepared by fluid - bed coating method. Pantoprazole enteric - coated pellets were encapsulated into hard capsules to obtain PECPC. Results The prepared PECPC were well re-sistant to acid in the artificial gastric juice and dissolved quickly and completely in the artificial intestinal liq-uid. Concl…查看全部>>
宋成刚;李洪程;王耀朋;刘彬;单波;李国亮
寿光富康制药有限公司，山东 寿光 262700寿光富康制药有限公司，山东 寿光 262700寿光富康制药有限公司，山东 寿光 262700寿光富康制药有限公司，山东 寿光 262700寿光富康制药有限公司，山东 寿光 262700寿光富康制药有限公司，山东 寿光 262700
医药卫生
泮托拉唑钠肠溶微丸胶囊流化床
PantoprazoleEnteric - coated pellet capsulesFluid - bed coating
《药学研究》 2014 (5)
276-278,3
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