药学研究Issue(6):359-361,372,4.
Btk抑制剂的研究进展
Research progress on Btk inhibitors
邓容 1赵利枝1
作者信息
- 1. 鲁南制药集团股份有限公司,山东 临沂276005
- 折叠
摘要
Abstract
Btk is necessary in B-cell antigen receptor( BCR)signaling pathway and cytokine-induced signal pathway in the macrophages. Btk inhibition has emerged as an attractive target for therapeutic intervention in human B-cell malig-nancies and autoimmune disorders. This review summarized the mechanism of Btk inhibitors and recent developments of Btk inhibitors already launched or in clinical trial.关键词
Btk/B细胞/淋巴瘤/类风湿性关节炎Key words
Btk/B-cell/Lymphoma/Rheumatoid arthritis分类
医药卫生引用本文复制引用
邓容,赵利枝..Btk抑制剂的研究进展[J].药学研究,2014,(6):359-361,372,4.