药学研究Issue(7)：379-381,388,4.
复方丹参片对类风湿性关节炎大鼠胫骨形态计量学静态参数的影响
Effect of Fufang Danshen Tablets on static bone histomorphology parameters of cancellous bone tissue in CIA rats
肖彦燊 1董文铭 1王亚海1
作者信息
- 1. 湛江中心人民医院骨科，广东 湛江 524037
- 折叠
摘要
Abstract
Objective To study the effect of Fufang Danshen Tablets against osteoporosis of CIA rats. Methods CIA rat model was established by injecting bovine type II collagen subcutaneously. Three groups including normal control group (n = 10),experimental control group(n = 12)and experimental group(n = 12)were built and the mice were treated with sterilized water or Fufang Danshen Tablets,respectively for 2 months. Parameters including wet weight,dry weight,length and circumference,as well as the static bone histomorphology parameters of the mice shin bone in each group were collected for analysis. Results The wet weight,dry weight and static bone histomorphology parameters of bone tissue in experimental and experimental control group were significantly lower than that in normal control group,the similar results were found be-tween experimental control group and experimental group. Conclusion Fufang Danshen Tablets can obviously inhibit bone erosion and osteoporosis in CIA rats,but further study was needed for clarifying the mechanism.关键词
复方丹参/类风湿性关节炎/骨质疏松/胶原诱导性关节炎Key words
Fufang Danshen/rheumatoid arthritis/Osteoporosis/CIA分类
医药卫生引用本文复制引用
肖彦燊,董文铭,王亚海..复方丹参片对类风湿性关节炎大鼠胫骨形态计量学静态参数的影响[J].药学研究,2014,(7):379-381,388,4.
