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枸杞多糖对自身免疫性卵巢早衰模型小鼠的保护作用

黄恬 郑晓霞 邱小华 王艳

药学研究Issue(8):437-440,4.
药学研究Issue(8):437-440,4.

枸杞多糖对自身免疫性卵巢早衰模型小鼠的保护作用

The protective effect of lycium barbarum polysaccharide on model of autoimmune premature ovarian failure in mice

黄恬 1郑晓霞 1邱小华 1王艳1

作者信息

  • 1. 汕头大学医学院第二附属医院,广东 汕头515041
  • 折叠

摘要

Abstract

Objective To evaluate the Protective effect of lycium barbarum Polysaccharide( LBP)on model of autoim-mune Premature ovarian failure in mice. Methods The model of autoimmune Premature ovarian failure was induced by PzP3 to simulate the Premature ovarian failure( POF)changes. The Protective effects of LBP were investigated in this mod-el. Results LBP treatment significantly imProved the estrous cycle disorder,reduced the levels of the serum AzPAb,follicle-stimulating hormone( FSH),enhanced the level of the serum estradiol( E2 )and gained weight between the 7 weeks to 8 weeks as comPared with the model grouP. Conclusion LBP offerred theraPeutic effect against PzP3-induced autoimmune Premature ovarian failure in mice.

关键词

枸杞多糖/卵巢早衰/小鼠

Key words

Lycium barbarum Polysaccharide/Premature ovarian failure/Mice

分类

医药卫生

引用本文复制引用

黄恬,郑晓霞,邱小华,王艳..枸杞多糖对自身免疫性卵巢早衰模型小鼠的保护作用[J].药学研究,2014,(8):437-440,4.

基金项目

广东省中医药局科研基金 ()

药学研究

2095-5375

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