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HPLC 法测定复方参花搽剂中苦参碱的含量

高云 郑祝华

药学研究Issue(9):519-521,3.
药学研究Issue(9):519-521,3.

HPLC 法测定复方参花搽剂中苦参碱的含量

Determination of matrine in Compound Shenhua Liniment by HPLC

高云 1郑祝华2

作者信息

  • 1. 泰安市中心医院,山东 泰安 271000
  • 2. 乳山市中医院儿科,山东 乳山 264500
  • 折叠

摘要

Abstract

Objective To establish an HPLC method for the determination of matrine in Compound Shenhua Liniment. Methods The column:Econobase C18 ,column temperature:28 ℃ ,The mobile phase:acetonitrile - 0. 1% phosphate(20:80),the flow rate:1. 0 mL·min - 1 . The detection wavelength was 210 nm. Results The linear range of matrine was 1. 038 ~ 20. 76 μg· mL - 1( r = 0. 999 4),the average recovery was 99. 35% ,the RSD of repeatability test was 1. 95%. Conclusion The method was simple and fast,the results were accurate and reproducible.

关键词

高效液相色谱/复方参花搽剂/苦参碱/含量测定

Key words

HPLC/Compound Shenhua Liniment/Matrine/Determination

分类

医药卫生

引用本文复制引用

高云,郑祝华..HPLC 法测定复方参花搽剂中苦参碱的含量[J].药学研究,2014,(9):519-521,3.

药学研究

2095-5375

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