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高效液相色谱法测定克林霉素磷酸酯片的含量

陈燕 郭琪 刘虹

药学研究Issue(2):78-79,2.
药学研究Issue(2):78-79,2.

高效液相色谱法测定克林霉素磷酸酯片的含量

Determination of Clindamycin Phosphate Tablets by HPLC

陈燕 1郭琪 1刘虹1

作者信息

  • 1. 潍坊市食品药品检验检测中心,山东 潍坊261061
  • 折叠

摘要

Abstract

objective To establish a method for the determination of Clindamycin Phosphate Tablets. Methods The HPLC method was performed on C8 column with a mobile phase of phosphate buffer-acetonitrile(73:27)and the detection wavelength was set at 210 nm. The contents were determined by external standard. Results The calibration curve was line-ar in the range of 0. 060~0. 60 mg·mL-1(R2 =0. 997 9). The average recovery was 98. 98% with RSD of 0. 46%. Con-clusion The method was simple,rapid and accurate. It can be used for the determination of Clindamycin Phosphate Tab-lets.

关键词

克林霉素磷酸酯片/高效液相色谱法/含量

Key words

Clindamycin Phosphate Tablets/HPLC/Content

分类

医药卫生

引用本文复制引用

陈燕,郭琪,刘虹..高效液相色谱法测定克林霉素磷酸酯片的含量[J].药学研究,2015,(2):78-79,2.

药学研究

2095-5375

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