药学研究Issue(5)：272-275,4.
近红外光谱分析技术在白芍水提过程中的在线控制研究
Resarch of online control of NIRS in the Radix paeoniae alba water extraction process
摘要
Abstract
To study a online analysis method of Radix paeoniae alba extraction process of Shenzhiling Oral Liquid with NIRS. Methods The study carried on under laboratory scale,recording near infrared spectroscopy of samples by using the ANTARIS II near infrared spectrometer and HPLC method was applied for determining paeoniflorin content in the sample. In order to establish quantitative analysis model,the spectral data and liquid phase data were fit by PLS. Results The study showed that the spectra based on OSC with mean center can obtain a good model in the optical spectrum and the model pa-rameters:RMSEC,R2cal ,R2val ,LVs were 0. 080 5,0. 968 4,0. 920 6,4,respectively. Conclusion This experiment of Radix paeoniae alba water extraction process of Shenzhiling Oral Liquid provided a new online monitoring method,and then provid-ed protection for the stability of product and the product quality.关键词
近红外光谱技术/白芍水提过程/芍药苷/定量分析/参枝苓口服液Key words
NIRS/Radix paeoniae alba water extraction process/Paeoniflorin/Quantitative analysis/Shenzhiling Oral Liquid分类
医药卫生引用本文复制引用
张慧,胡甜,臧恒昌..近红外光谱分析技术在白芍水提过程中的在线控制研究[J].药学研究,2015,(5):272-275,4.基金项目
山东省自主创新专项国家中药新药“参枝苓口服液”产业化开发项目 （）
