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坎地沙坦联合曲美他嗪治疗原发性高血压左室肥厚的临床观察

王春梅 文军 丁润会 刘叶 嵇诚 郭景华 袁志勇

药学研究Issue(5):304-305,2.
药学研究Issue(5):304-305,2.

坎地沙坦联合曲美他嗪治疗原发性高血压左室肥厚的临床观察

Clinical observation of Candesartan combined with Trimetazidine on treating ventriculus sinister hypertrophy of essential hypertension

王春梅 1文军 1丁润会 1刘叶 1嵇诚 1郭景华 1袁志勇1

作者信息

  • 1. 秦皇岛市海港医院,河北 秦皇岛066000
  • 折叠

摘要

Abstract

Objective To observe the curative effect of Candesartan combined with Trimetazidine on treating ventricu-lus sinister hypertrophy of essential hypertension. Methods 115 cases of essential hypertension patients were divided into two groups randomly. A group was treated by Candesartan orally and B group was treated by Candesartan combined with Tri-metazidine. The antihypertensive effect and changes of echocardiogram index of two groups were compared. Results Com-pared with pretherapy,the blood pressures of patients in two groups were obviously reduced(P<0. 05),but the antihyper-tensive effects had no statistics difference(P>0. 05). LVEDd,LVPWT,IVST,LVMI,LVEF and E/A in two groups were obviously improved and B group was all better than A group(P<0. 05). Conclusion Compared with treating only with Candesartan,Candesartan combined with Trimetazidine can obviously reverse the ventriculus sinister hypertrophy of essential hypertension and improve heart function.

关键词

坎地沙坦/曲美他嗪/高血压/左室肥厚

Key words

Candesartan/Trimetazidine/Hypertension/Ventriculus sinister hypertrophy

分类

医药卫生

引用本文复制引用

王春梅,文军,丁润会,刘叶,嵇诚,郭景华,袁志勇..坎地沙坦联合曲美他嗪治疗原发性高血压左室肥厚的临床观察[J].药学研究,2015,(5):304-305,2.

药学研究

2095-5375

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