药学研究Issue(7)：384-386,3.
利用近红外光谱技术快速鉴别厄贝沙坦分散片
Application in identification of Irbesartan Dispersible Tablets with near - infrared spectroscopy technology
闫研 1殷果 1刘凯双 1王珏 1王铁杰1
作者信息
- 1. 深圳市药品检验所，深圳药品质量标准研究重点实验室，广东 深圳 518057
- 折叠
摘要
Abstract
Objective To develop methods for rapid identification of Irbesartan Dispersible Tablets by Near - infrared (NIR)spectroscopy analytical technology and chemometrics. Methods NIR spectrum of Irbesartan Dispersible Tablets were collected by a fiber optic probe. The conformity test model was performed by comparing consistency index(CI)value and CI limit. The quick compare model was established through the correlation coefficient method. Results The conformity test model and quick compare model can rapidly identify and accurately distinguish Irbesartan Dispersible Tablets(manufac-tured by A)from similar products of other manufacturers. The CI value of the validation samples from other manufactures beyond the limit of 7. 0. Compared with the reference sample,the correlation coefficient(R2 )were less than 97% . Conclu-sion The NIR methods were simple and rapid,which can be used in quick identification of Irbesartan Dispersible Tablets (manufactured by A)in mobile lab.关键词
厄贝沙坦分散片/近红外光谱/一致性检验/相关系数/快速鉴别Key words
Irbesartan Dispersible Tablets/Near - infrared(NIR)spectroscopy/Conformity test/Correlation coeffi-cient/Quick identification分类
医药卫生引用本文复制引用
闫研,殷果,刘凯双,王珏,王铁杰..利用近红外光谱技术快速鉴别厄贝沙坦分散片[J].药学研究,2015,(7):384-386,3.
