药学研究Issue(7):420-421,424,3.
低分子肝素药理学机制及适应证研究进展
Research progress on pharmacological mechanism of LMWH and its clinical indications
刘晋仙 1李玮涛 1张在忠 2李荣 2陈少鹏2
作者信息
- 1. 东营市食品药品检验中心,山东 东营 257091
- 2. 东营天东制药有限公司,山东 东营 257067
- 折叠
摘要
Abstract
Low - molecular - weight heparin(LMWH)is obtained by various methods of fractionation or depolymerisa-tion of polymeric heparin. Compare to unfractionated heparin(UFH),LMWH have relatively smaller molecular weight,better anti - Xa activity,greater bioavailability at low doses,longer half - life and more predictable anticoagulant response when administered in fixed doses. This article described the pharmacological mechanism of LMWH and their clinical indications.关键词
低分子肝素/抗凝血/抗血栓/适应证Key words
Low - molecular - weight heparin/Anticoagulation/Antithrombosis/Indication分类
医药卫生引用本文复制引用
刘晋仙,李玮涛,张在忠,李荣,陈少鹏..低分子肝素药理学机制及适应证研究进展[J].药学研究,2015,(7):420-421,424,3.