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有机磷农药对男性生育功能的影响

郑立宏 杨丹 高晓勤

山东医药Issue(9):23-24,33,3.
山东医药Issue(9):23-24,33,3.DOI:10.3969/j.issn.1002-266X.2014.09.008

有机磷农药对男性生育功能的影响

Influence of organophosphorus pesticide on male fertility

郑立宏 1杨丹 2高晓勤3

作者信息

  • 1. 贵阳护理职业学院,贵阳550081
  • 2. 贵阳医学院外科教研室
  • 3. 遵义医药高等专科学校
  • 折叠

摘要

Abstract

Objective To discuss the influence of organophosphorus pesticide on male fertility .Methods The rou-tine examination of male semen was conducted in the observation group of 45 cases who were exposed to organophosphorus pesticide and the control group of 25 cases with non-contact.And then the apoptosis of sperm was examined by terminal de-oxynucleotidyl transferase mediated deoxyuridine triphophate-biotin nick end labeling ( TUNEL) .Results The sperm con-centration of the observation group was significantly lower than that of the control group .Sperm motility index ( including a grade sperm rate , b-sperm rate, c-sperm rate and d-sperm rate)and sperm motility assessment projects (including curve speed, line speed, average path velocity and average moving angle ) were significantly lower , but the apoptosis rate was higher in the observation group than those of the control group , significant differences were found (all P<0.01).Conclu-sions That Long-term exposure to organophosphate pesticides can lead semen quality to decline and sperm apoptosis to in -crease, which would make male infertility .

关键词

生育力/有机磷农药/男性

Key words

fertility/organophosphorus pesticides/male

分类

医药卫生

引用本文复制引用

郑立宏,杨丹,高晓勤..有机磷农药对男性生育功能的影响[J].山东医药,2014,(9):23-24,33,3.

基金项目

贵阳市科技局科技计划项目[筑科社[2012]1号]。 ()

山东医药

OA北大核心CSTPCD

1002-266X

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