山东医药Issue(9):23-24,33,3.DOI:10.3969/j.issn.1002-266X.2014.09.008
有机磷农药对男性生育功能的影响
Influence of organophosphorus pesticide on male fertility
摘要
Abstract
Objective To discuss the influence of organophosphorus pesticide on male fertility .Methods The rou-tine examination of male semen was conducted in the observation group of 45 cases who were exposed to organophosphorus pesticide and the control group of 25 cases with non-contact.And then the apoptosis of sperm was examined by terminal de-oxynucleotidyl transferase mediated deoxyuridine triphophate-biotin nick end labeling ( TUNEL) .Results The sperm con-centration of the observation group was significantly lower than that of the control group .Sperm motility index ( including a grade sperm rate , b-sperm rate, c-sperm rate and d-sperm rate)and sperm motility assessment projects (including curve speed, line speed, average path velocity and average moving angle ) were significantly lower , but the apoptosis rate was higher in the observation group than those of the control group , significant differences were found (all P<0.01).Conclu-sions That Long-term exposure to organophosphate pesticides can lead semen quality to decline and sperm apoptosis to in -crease, which would make male infertility .关键词
生育力/有机磷农药/男性Key words
fertility/organophosphorus pesticides/male分类
医药卫生引用本文复制引用
郑立宏,杨丹,高晓勤..有机磷农药对男性生育功能的影响[J].山东医药,2014,(9):23-24,33,3.基金项目
贵阳市科技局科技计划项目[筑科社[2012]1号]。 ()