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血尿酸水平与大面积脑梗死的相关性

陈艳 王灿 崔凌凌 李鑫德 王雪峰 李长贵

山东医药Issue(17):7-8,11,3.
山东医药Issue(17):7-8,11,3.DOI:10.3969/j.issn.1002-266X.2014.17.003

血尿酸水平与大面积脑梗死的相关性

Correlation between blood uric acid level and massive cerebral infarction

陈艳 1王灿 1崔凌凌 1李鑫德 1王雪峰 1李长贵1

作者信息

  • 1. 青岛大学医学院附属医院,山东青岛266003
  • 折叠

摘要

Abstract

Objective To investigate the relationship between the blood uric acid ( BUA) level and massive cerebral infarction.Methods Blood uric acid ( BUA), fasting plasma glucose ( FPG), triglycerides ( TG), total cholesterol ( TC) , low-density lipoprotein cholesterol ( LDL-C) and the infarction size were detected in 95 new cases of patients with massive cerebral infarction ( observation group ) and 95 healthy controls ( control group ) , and then the relationship between the BUA level and massive cerebral infarction was analyzed .Results The levels of BUA, FPG, TG, TC, and LDL-C were significantly higher in the observation group than those of the control group (all P<0.01).Multivariate Logistic re-gression analysis showed that the increased BUA level was the risk factor for the cerebral infaction (OR=1.005, 95%CI=1.002-1.008, P=0.001), and the larger the infarction size is, the higher the BUA level (P<0.05).Conclusions Hyperuricemia is an independent risk factor for massive cerebral infarction , and cerebral infarction area is positively cor-related with BUA level .

关键词

脑梗死/血尿酸/危险因素

Key words

massive cerebral infarction/blood uric acid/risk factors

分类

医药卫生

引用本文复制引用

陈艳,王灿,崔凌凌,李鑫德,王雪峰,李长贵..血尿酸水平与大面积脑梗死的相关性[J].山东医药,2014,(17):7-8,11,3.

基金项目

国家自然科学基金资助项目(81070686,31371272);山东省自然科学基金重点项目(ZR2010HZ001)。 ()

山东医药

OA北大核心CSTPCD

1002-266X

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