山东医药Issue(19)：1-3,3.DOI:10.3969/j.issn.1002-266X.2014.19.000
颞叶癫痫发作期患者过度放电起始区及脑电的传递方向
Directional transfer pattern of seizure EEG recording from Temporal Lobe Epilepsy patient s
摘要
Abstract
Objective For the initiation, and the directional transfer of excessive discharge from epileptic foci to other brain regions, directional transfer pattern of temporal lobe epilepsy EEG was studied .Methods 16 channel EEG data,which was recorded from eight cases of temporal lobe epilepsy group and eight cases of the control group , was calculated the directional transfer function matrix in the frequency domain by Granger causality analysis method .Then,the DTF matrix was verified the au-thenticity of causality, and was excluded pseudo-causality.Causal flow is obtained by calculating the DTF matrix, in order to de-termine the initiation, as well as research EEG directional transfer pattern from initiation to other brain regions .Results there is significant difference between the DTF value (0.06545 ±00.152 ) of the temporal lobe of initiation in epilepsy group and the DTF value (0.042863 ±0.0064) of the left temporal lobe o,r the DTF value (0.042863 ±0.0064) of the right temporal lobe in the normal control group.The causal flow results of the temporal lobe epilepsy group are as follows:the regions of causal flow val-ue>0.5:the regions of 2 cases'are located on channels F7 and T3 in left tempora, 2 cases'are located on channel T3 and T5 in the left posterior temporal,1 case's is located on channel T5 in the left anterior temporal,1 case's are located on channel F7,T3 and T5 in the left anterior temporal.1 case's is located on channel T4 in right middle temporal, 1 case's are located on channel T4 and T6 in right posterior temporal.The region of causal flow value<-0.5:the regions of 6 cases'are located on the channel Fp1, Fp2 or F3, F4.There is no region of the causal flow values <-0.5 in two patients.The normal control group:there is no significant causal connection between each channel.Conclusions The initiation is located in the temporal lobe.Excessive dis-charge transferred from the the temporal region to other brain regions , mainly in the prefrontal, frontal.关键词
颞叶癫痫/脑电/Granger因果分析/定向传递函数/因果流Key words
temporal lobe epilepsy/directional transfer pattern of EEG seizure/Granger causality analysis/direction-al transfer function/causal flow分类
医药卫生引用本文复制引用
裘志军,陈旨娟,田心..颞叶癫痫发作期患者过度放电起始区及脑电的传递方向[J].山东医药,2014,(19):1-3,3.基金项目
国家自然科学基金资助项目（91132722）。 （）
