山东医药Issue(7)：23-25,3.DOI:10.3969/j.issn.1002-266X.2015.07.008
经皮腔内治疗在高血压合并动脉粥样硬化性肾动脉狭窄老年患者中的应用效果及安全性
Safety and effectiveness of endovascular intervention therapy for atherosclerotic renal artery stenosis in old patients with hypertension
摘要
Abstract
Objective To observe the safety and effectiveness of endovascular interventional treatment for atherosclerot -ic renal artery stenosis ( ARAS) in old patients with hypertension .Methods Endovascular interventional treatments were performed in 45 old patients with hypertension combined with ARAS ( luminal narrowing≥70%) .The therapeutic effects were analyzed by means of blood pressure , types of hypotensors , renal function changes before and after therapy in average 12-month follow-up after operation .Results The percutaneous transluminal interventional treatment was successfully per -formed in 51 renal arteries of 45 patients.Five days after intervention , the systolic blood pressure decreased to (157.78 ± 12.36) mmHg, diastolic blood pressure decreased to (94.87 ±6.12) mmHg, and serum creatine ( Scr) was (161.15 ± 11.37)μmol/L.There was significant difference in the diastolic blood pressure as compared with that before treatment (P<0.05).Six months after intervention, the systolic blood pressure decreased to (145.64 ±11.57) mmHg, the diastolic blood pressure decreased to (77.42 ±7.63) mmHg, and Scr was (159.18 ±13.45)μmol/L.There were significant differences in the systolic and diastolic blood pressure as compared with that before treatment (all P<0.05).During the follow-up period for 12 months, the systolic blood pressure decreased to (142.36 ±9.79) mmHg, the diastolic blood pressure decreased to (74.97 ±8.82) mmHg, and Scr was (160.86 ±9.73) μmol/L.There were significant differences in the systolic and dias-tolic blood pressure as compared with that before treatment (all P<0.05).The number of hypotensors reduced from (2.96 ± 1.07) to (1.80 ±0.23) (P<0.05).All patients did not have serious complications , and 4 patients due to renal artery stent restenosis were performed with percutaneous transluminal renal angioplasty again .Conclusion The medium-term results of endovascular interventional treatment for ARAS in old patients with hypertension are safe and satisfactory .关键词
高血压/动脉粥样硬化/肾动脉狭窄/经皮腔内肾动脉成形术/经皮肾动脉支架置入术Key words
hypertension/atherosclerosis/renal arterial stenosis/percutaneous transluminal renal angioplasty/per-cutaneous transluminal renal artery angioplasty and stenting分类
医药卫生引用本文复制引用
王凯,蒋国民,田丰,李绍钦,贾中芝,恽文伟..经皮腔内治疗在高血压合并动脉粥样硬化性肾动脉狭窄老年患者中的应用效果及安全性[J].山东医药,2015,(7):23-25,3.基金项目
南京医科大学科技发展基金项目（2012NJMU137）。 （）
