肾癌组织 EphA2、E-cadherin 表达及其与肾癌临床病理特征的关系OA北大核心CSTPCD
Expression of EphA2, E-cadherin in renal cell carcinoma and its relationship with clinical pathological features of patients
目的：探讨Eph受体酪氨酸激酶A2（EphA2）及E-钙黏蛋白（E-cadherin）在肾癌组织中的表达及其与肾癌临床病理特征的关系。方法选择52例肾癌患者的手术标本，采用免疫组化SP法检测肾癌组织EphA2及E-cadherin蛋白的表达，计算每张切片的阳性细胞百分数及HSCORE分值。分析EphA2表达、E-cadherin表达与患者临床病理特征（包括年龄、性别、TNM分期、肿瘤直径、病理类型）的关系，计算3年生存率，应用COX比例风险模型分…查看全部>>
Objective To investigate the expression of Eph receptor tyrosine kinase-A2 (EphA2) and E-cadherin in renal cell carcinoma ( RCC) and its relationship with clinical pathological features of patients .Methods The expression of EphA2 and E-cadherin was detected by immunohistochemical SP method in the tumor tissues from 52 RCC patients .The HSCORE score and percentage of positively stained cells were calculated .The relationships between the expression of E-phA2…查看全部>>
张俊霞;徐金升;白亚玲;崔立文;张慧然;张胜雷
河北医科大学第四医院，石家庄050011河北医科大学第四医院，石家庄050011河北医科大学第四医院，石家庄050011河北医科大学第四医院，石家庄050011河北医科大学第四医院，石家庄050011河北医科大学第四医院，石家庄050011
医药卫生
肾癌Eph受体酪氨酸激酶A2E-钙黏蛋白预后
kidney neoplasms , kidney carcinomaEph receptor tyrosine kinase-A2E-cadherinprognosis
《山东医药》 2015 (10)
4-6,3
河北省科技计划资助项目（122777219）。
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