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地黄饮子含药血清对海马脑片SD F-1的影响

王倩 范文涛 贺又舜

陕西中医Issue(3):373-375,3.
陕西中医Issue(3):373-375,3.DOI:10.3969/j.issn.1000-7369.2015.03.058

地黄饮子含药血清对海马脑片SD F-1的影响

Effect of Dihuang Yinzi protein on hippocampal slices of SDF-1 in rats

王倩 1范文涛 2贺又舜1

作者信息

  • 1. 湖南中医药大学 长沙410208
  • 2. 陕西中医学院 咸阳712046
  • 折叠

摘要

Abstract

Objective:To study Dihuang Yinzi protein in rat hippocampal slices of SDF‐1 .Methods:18 SD rats , rats with ether anesthesia ,separation of hippocampus ,training 2 weeks later ,divided into the control group (group HOTC) and low oxygen lack of sugar group (OGD group) .Using Dihuang Yinzi drug‐containing serum cultured hipp‐ocampal slices ,observation of Dihuang Yinzi drug‐containing serum affect hippocampal slices of SDF‐1 .Results :The study found that with Dihuang Yinzi drug‐containing serum training rats ,can significantly improve the ischemia and hy‐poxia of brain slice of SDF‐1 and CXCR4 protein content ,compared with the control group with significant difference ,Di‐huang Yinzi can promote the expression of ischemia area SDF‐1 ,to further promote the low oxygen sugar area brain nerve regeneration ability .Conclusion :DiHuang YinZi medicated serum can effectively improve the ischemia anoxic zone slices SDF‐1 content and further improve the cerebral ischemic anoxia ability ,through the SDF‐1/CXCR4 signaling pathway to promote brain nerve regeneration .

关键词

@地黄饮子/动物 ,实验/大鼠

Key words

Dihuang/Yinzi/Animal ,experiment/Rats

分类

医药卫生

引用本文复制引用

王倩,范文涛,贺又舜..地黄饮子含药血清对海马脑片SD F-1的影响[J].陕西中医,2015,(3):373-375,3.

基金项目

陕西省科技厅资助项目 ()

陕西中医

OACSTPCD

1000-7369

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