陕西中医Issue(5)：624-625,2.DOI:10.3969/j.issn.1000-7369.2015.05.048
咸阳地产山楂对小鼠高脂血症预防作用的实验研究
Prevention Effects of Xianyang Local Hawthorn in Mice with Experimental Hyperlipidemia
摘要
Abstract
Objective:To explore the effects of Xianyang local hawthorn on serum level of Triglyceride and To‐tal cholesterol in mice with experimental hyperlipidemia .Methods :We adopted the animal model ,60 healthy Kunming male mice were randomLy divided into blank control group (group A) ,model control group(group B) and hawthorn juice low dose group (group C ) ,hawthorn juice middle dose group (group D) and hawthorn juice large group (group E) with 12 mice in each group .Using the animal models which were fed by high fat diet except group A ,4 weeks in total .Except group A and group B ,the mice in other groups also were given hawthorn juice by gavage once daily .At the day after suc‐cessfully modeling ,the content of serum TG and TC of all mice were tested ,and all results were statistically analyzed by means of t‐test .Results:In the comparison with group A ,the TG and TC levels of mice in group B increased significant‐ly (P<0 .05) .The content of TG and TC in group C ,D and E were lower than that of group B .Conclusions :By reducing the levels of TG and TC ,Xianyang local hawthorn can prevent the occurrence of hyperlipemia .关键词
高脂血症/中医药疗法/山楂/动物实验/小鼠Key words
Hyperlipidemias/traditional Chinese medicine therapy/Crataegus pinnatifida/Animal experi-mentation/Mice分类
医药卫生引用本文复制引用
屈红艳,王瑞辉,李佩佩,杜旭..咸阳地产山楂对小鼠高脂血症预防作用的实验研究[J].陕西中医,2015,(5):624-625,2.基金项目
陕西省咸阳市科技计划项目［XK0816-（8）］ （）
