山西中医学院学报Issue(1)：24-26,3.
龙葵正丁醇提取物对Lewis肺癌移植瘤生长的影响
Effects of n-butanol extract from Solanum Nigrum L.on metastatic tumor growth
摘要
Abstract
Objective:To observe the inhibiting effects of n-butanol extract from Solanum Nigrum L.on metastatic tumor growth in mice with lewis lung cancer. Methods:40 C57BL/6J mice set up Lewis Lung tumor model were randomly divid-ed into tumor-burdened blank control group,cyclophosphamide group,n-butanol extract high,medium and low dosage group with 8 mice in each group. The mice were given drug respectively in 15 days and subsequently were killed. Tumor tissue were striped and weighed so as to calculate the tumor growth inhibition rate. Mice′s thymus and spleen were dis-sected and weighed so as to calculate index of thymus and spleen. Results:The inhibition rate of n-butanol extract high, medium and low dosage group were 32.14%,13.93%and 15.36%. The thymus index growth rate of n-butanol extract high dosage group was 134.31%;the spleen index growth of n-butanol extract medium dosage was 128.73%. Conclusion:The n-butanol extract from Solanum nigrum L.has certain inhibition effect on lewis lung cancer growth and the extract can in-crease mice′s thymus and spleen index.关键词
龙葵/正丁醇/抑瘤率/胸腺指数/脾脏指数Key words
Solanum nigrum L./n-butanol/inhibition rate/thymus index/spleen index分类
医药卫生引用本文复制引用
金旺,高聚伟,潘磊,陈培丰..龙葵正丁醇提取物对Lewis肺癌移植瘤生长的影响[J].山西中医学院学报,2015,(1):24-26,3.基金项目
浙江省中医药科技计划项目 （）
