上海针灸杂志Issue(12)：1083-1085,3.DOI:10.13460/j.issn.1005-0957.2014.12.1083
TRPV1在电针调节胃运动中的作用
Role of TRPV1 in the Regulation of Gastric Motility by Electroacupuncture
摘要
Abstract
ObjectiveTo discuss the role of transient receptor potential vanilloid 1 (TRPV 1) in the regulation effect of electroacupuncture on gastric motility.MethodTRPV1 gene knock-out mice (KO mice) and wild-type C57BL/6 mice (WT mice) were selected to receive acupuncture at Zusanli (ST36),Quchi (LI11), Zhongwan (CV12), and Weishu (BL21), and the intragastric pressure was observed before and after acupuncture.ResultElectroacupuncture at Zusanli caused both excitation and inhibition in WT mice, predominated by mild excitation, while electroacupuncture at Weishu, Quchi and Zhongwan all caused inhibition effect; in the KO mice, electroacupuncture at Zusanli, Quchi, Zhongwan, and Weishu all inhibited gastric motility.Conclusion TRPV1 bears certain regulating effect on gastric motility, andacupuncture can inhibit the gastric motility in TRPV gene KO mice.关键词
TRPV1/电针/胃运动/小鼠Key words
Transient receptor potential vanilloid 1 (TRPV1)/Electroacupuncture/Gastric motility/Mouse分类
医药卫生引用本文复制引用
汪一丹,曹新,冯虹,余芝,徐斌..TRPV1在电针调节胃运动中的作用[J].上海针灸杂志,2014,(12):1083-1085,3.基金项目
国家重点基础研究发展计划(2011CB505206) （2011CB505206）
国家自然科学基金资助项目(81202744） （）
中国中医科学院自主选题项目(ZZKF06003) （ZZKF06003）
江苏省高校自然科学研究计划项目(11KJB360008) （11KJB360008）
江苏省特色优势学科资助 （）
江苏省高校青蓝工程优秀科技创新团队资助 （）
