世界中医药Issue(6):754-755,758,3.DOI:10.3969/j.issn.1673-7202.2014.06.019
前列地尔联合百令胶囊治疗急性肾损伤435例临床研究
Clinical Research on Alprostadil Combined with Bailing Capsule in Treating 435 Cases of Acute Kidney Injury
唐瑭 1陈德森 2彭吉霞2
作者信息
- 1. 湖北医药学院附属太和医院,十堰,442000
- 2. 湖北医药学院机能实验室,十堰,442000
- 折叠
摘要
Abstract
Objective:To observe the therapeutic effect of Alprostadil injection combined with Bailing capsule on patients with acute kidney injury and explore its mechanism of action.Methods:Four hundred and thirty six cases of acute kidney injury were randomly di-vided into alprostadil group,bailing capsule group,combined treatment group.Except from the routine treatment,patients in the three groups were respectively given Alprostadil Injection,bailing capsule and the combined treatment for 4 weeks.The levels of urinary albu-min excretion rate,serum creatinine,urea,cystatin C before and after treatment were measured.Results:Compared with the only appli-cation of Alprostadil injection or corbrin capsule,the combination therapy further decreased the levels of the urinary albumin excretion rate,creatinine,urea,Cystatin C (P<0.05).Conclusion:Alprostadil injection combined with Bailing capsule is effective for acute kid-ney injury is reliable,and has stronger renal protective effect than the single use of one drug.关键词
急性肾损伤/尿微量白蛋白排泄率/血清肌酐/尿素/胱抑素C/前列地尔注射液/百令胶囊Key words
Acute kidney injury/Urinary albumin excretion rate/Serum creatinine/Urea/Cystatin C/Alprostadil injection/Bailing capsule分类
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唐瑭,陈德森,彭吉霞..前列地尔联合百令胶囊治疗急性肾损伤435例临床研究[J].世界中医药,2014,(6):754-755,758,3.