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多囊卵巢综合征中医证型与糖代谢及IGF-I、IGFBP-1相关性的研究

郑洁莉 徐莉

世界中医药Issue(7):889-891,894,4.
世界中医药Issue(7):889-891,894,4.DOI:10.3969/j.issn.1673-7202.2014.07.017

多囊卵巢综合征中医证型与糖代谢及IGF-I、IGFBP-1相关性的研究

Study on the Relationship between TCM Differentiation Types of Polycystic Ovary Syndrome and Glycometabolism,IGF-I and IGFBP-1

郑洁莉 1徐莉1

作者信息

  • 1. 广东省第二中医院治未病中心,广州,510095
  • 折叠

摘要

Abstract

To investigate the regularities of distribution of TCMdifferentiation types of polycystic ovary syndrome,and its re-lationship with glycometabolism and inflammatory factors IGF-I and IGFBP-1 .Methods:The TCM differentiation types of 1 20 cases of PCOS patients was investigated,and at the same time their BMI,homeostasis model assessment insulin resistance and insulin growth fac-tor-I(IGF-I),insulinlikegrowthfactorbindingimmunoglobulin-1(IGFBP-1) ofpatientsweremeasured.Therelationshipbetween the TCM differentiation of polycystic ovary syndrome and glycometabolism,IGF-I and IGFBP-1 were explored.Results:TCM differenti-ation types included kidney deficiency,phlegm-dampness due to deficiency of the spleen,stagnation of liver qi,and the constituent ratio was 35%,33%,and 32%.The difference in all the three groups was not significant,P>0.05.The levels of BMI,FINS,Homa-IR of phlegm-dampness due to deficiency of the spleen were higher than those of the other two groups,and the differences remained signifi-cant,P<0.05 .The level of IGFBP-I of phlegm-dampness due to deficiency of the spleen was lower than that of the other two,and the differences remained significant,P<0.05 .The level of IGF-I phlegm-dampness due to deficiency of the spleen was higher than that of the other two,and the difference was not significant,P>0.05.Conclusion:The TCMdifferentiation types of polycystic ovary syndrome mainly included kidney deficiency,phlegm-dampness due to deficiency of the spleen,stagnation of liver qi.The syndrome of phlegm-dampness due to spleen deficiency was relevant to insulin resistance and decline of IGFBP-1 .

关键词

多囊卵巢综合征/中医证型/胰岛素抵抗

Key words

Polycysticovarysyndrome/TCMdifferentiation/Insulinresistance

分类

医药卫生

引用本文复制引用

郑洁莉,徐莉..多囊卵巢综合征中医证型与糖代谢及IGF-I、IGFBP-1相关性的研究[J].世界中医药,2014,(7):889-891,894,4.

基金项目

广东省中医药局课题 ()

世界中医药

OACHSSCDCSTPCD

1673-7202

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