世界中医药Issue(8)：1073-1075,3.DOI:10.3969/j.issn.1673-7202.2014.08.031
消渴丸对GK大鼠心、肾影响的研究
Research of GK rats Heart and Kidney Impacted by Xiaoke Wan
摘要
Abstract
Objective:To compare the impact on GK ratsheart and kidney by TCM component of Xiaoke Wan,the chemical component (Glibenclamide)of Xiaoke Wan and Xiaoke Wan,in order to explore the role of the TCMcomponent in Xiaoke Wan.Methods:After 24 weeks respective administration of the traditional component of Xiaoke Wan,the chemical component of Xiaoke Wan and Xiaoke Wan,the GK rats were sacrificed,and a series of index were measured such as the microstructure of the heart and kidney,the subcellular structure of the heart and kidney.Results:The microstructure of the heart and kidney,and the subcellular structure of heart and kidney were amel-iorated by the TCM component of Xiaoke Wan and Xiaoke Wan,and the effect was dose-dependent.Conclusion:In this study,the TCM component of Xiaoke Wan plays an important role of reducing the heart and kidney complication of diabetes mellitus,the mechanism of which needs further research.关键词
消渴丸/格列本脲/消渴丸中药组份/GK大鼠/超微结构Key words
Xiaoke Wan/Glibenclamide/TCM component of Xiaoke Wan/GK rats/Subcellular structure分类
医药卫生引用本文复制引用
邹琦,刘菊妍,吴燕梅,周杰..消渴丸对GK大鼠心、肾影响的研究[J].世界中医药,2014,(8):1073-1075,3.基金项目
2006年粤港关键领域重点突破项目“华南创新中药研究开发与技术服务中心（平台） （）
