世界中医药Issue(10)：1334-1337,4.DOI:10.3969/j.issn.1673-7202.2014.10.024
巴西莓对急性酒精中毒小鼠的解酒及保肝作用研究
The Detoxication and Protective Effect of Acai Against Acute Alcohol Toxication and Acute Alcohol Liver Injury in Mice
王林元 1陈绍红 1屈胜胜 1李伟 1黄银峰 1张建军1
作者信息
摘要
Abstract
Objective:To study the effects of Acai ( Euterpe Oleraceae Mart.) on acute alcohol toxication and protective effect on acute alcohol liver injury in mice.Methods:Acute alcohol toxication animal model was established by alcohol gavaged (50%at 15 mL/kg) . The acute liver injury animal model was established by alcohol gavaged (50%at 12 mL/kg).The serum levels of ALT,AST and the con-tent of MDA,TG,the activity of GSH,SOD in liver of the mice were measured.Results:Acai can shorten the recovery time of rightening reflex compared with the model groups (P<0.05).The groups of Acai significantly reduced the levels of serum ALT,AST(P<0.01) which were induced by ethanol,and the content of MDA,TG (P<0.05),the activity of GSH in liver were significantly different com-pared with those of the model groups ( P<0.05) .Conclusion:Acai has effect of relieving alcohol toxicity and a protective effect on acute alcohol liver injury in mice and its mechanism may relate to the capacity of anti-oxidant.关键词
巴西莓/酒精中毒/肝损伤/抗氧化Key words
Acai/Ethanol/Toxication/Liver injury/Anti-oxidant分类
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王林元,陈绍红,屈胜胜,李伟,黄银峰,张建军..巴西莓对急性酒精中毒小鼠的解酒及保肝作用研究[J].世界中医药,2014,(10):1334-1337,4.
