世界中医药Issue(12)：1572-1574,1580,4.DOI:10.3969/j.issn.1673-7202.2014.12.004
恒河猴感觉皮层手区切除后的脑功能重组
Rhesus sensory cortex hand area after resection of brain functional reorganization
摘要
Abstract
Objective:To study the effect of removal of the hand area in rhesus monkeyssensory cortex on the reorganization of brain function,and explore in pathological situations whether the cerebral cortex would make a compensation for regulating the sensory function of face,mouth and the hand area,so as to reveal possible biological mechanisms of the “diseases of the face and mouth apply Hegu”the-ory.Methods:To obtain experimental models by Surgically removing the rhesusthe hand area of sensory cortex,search for neuron dis-charge of rhesus monkeyssensory cortex through the extracellular recording by microelectrode,and observe changes in neurons periphery reception field within the area of the hand and face in sensory cortex.Results:Three months after resection of rhesus monkeyshand area in sensory cortex,those originally reacted to facial stimulation now react to both the stimulations from face and hands.Conclusion:1)The lose of the hand area in sensory cortex lead to functional reorganization both in the face and forearm area.At the same time,the face and forearm area are gradually expand to the hand area.2)Functional reorganization seems to have a certain tendency,that is to say the functional reorganization between face area and hand area are stronger then the functional reorganization between forearm area and hand area.3)Under pathological condition,the functional reorganization of hand area and face area in cerebral cortex maybe the biological mechanism of the “diseases of the face and mouth apply Hegu”.关键词
恒河猴/皮层切除/面口合谷收/脑功能重组Key words
Rhesus monkeys/Sensory cortex resection/Neurons discharge/Brain function reorganization/Diseases of the face and mouth apply Hegu分类
医药卫生引用本文复制引用
黄倩兰,阳仁达,周灿,谢力..恒河猴感觉皮层手区切除后的脑功能重组[J].世界中医药,2014,(12):1572-1574,1580,4.基金项目
国家重点基础研究发展计划（“973”计划）项目经脉体表特异性联系的生物学机制及针刺手法量效关系的研究 （）
